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Effects of TMEM216 on the transcriptomes of E12 mice embryos

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RNA-seq analysis of tissues from E12 Tmem216+/+ and Tmem216-/- embryos were performed to identify the mechanism underlying TMEM216 affecting ciliogenesis. After quantified by TBS380, paired-end RNA-seq sequencing library was sequenced with the Illumina HiSeq xten. Our results demonstrate that TMEM216 deficiency impairs Hh signaling pathway of mice. mRNA profiles of E12 Tmem216+/+ and Tmem216-/- embryos

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