Expression data from DC1 purified from spleens of WT, WT Irf8VENUS+, and Batf3-/- Irf8VENUS+ mice.. Expression data from DC1 purified from spleens of WT, WT Irf8VENUS+, and Batf3-/- Irf8VENUS+ mice.
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下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA435630
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资源简介：
Batf3-/- mice have impaired development of DC1 . However, DC1 development is restored in Batf3-/- mice containing an Irf8VENUS transgene. Even though DC1 development was restored in these mice, they were still unable to reject a transplanted immunogenic fibrosarcoma, indicating that there are some functions of Batf3-dependent dendritic cells that are not restored by the Irf8VENUS transgene. Overall design: Microarray analysis was performed on DC1 sorted from skin draining lymph nodes of WT Irf8VENUS, and Batf3-/- Irf8VENUS mice, all on C57Bl/6j background. Migratory and resident DC1 were analyzed for both genotypes.
创建时间：
2018-02-22
