Aggregated proteome of MDK model mice

NIAID Data Ecosystem2026-05-02 收录

神经退行性机制

蛋白质组学靶点发现

数据链接：

https://www.omicsdi.org/dataset/pride/PXD045746 数据链接链接失效反馈

官方服务：

资源简介：

MDK is a heparin-binding growth factor and found to be the Aβ associated protein. Through aggregated proteome, we aim to identify DE proteins more associated with plaques by MDK knockout.

创建时间：

2025-07-16

Examination of gene expression in cerebellum and hippocampus for mouse C57BL/6J WT and nmf205-/-

神经退行性机制

细胞应激通路

Ribosome stalling during translation has recently been shown to cause neurodegeneration, yet the signaling pathways triggered by stalled elongation complexes are unknown. To investigate these pathw

NIAID Data Ecosystem100

AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons. AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons

神经退行性机制

功能障碍研究

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem40

Loss of TREM2 reduces hyperactivation of progranulin deficient microglia but not lysosomal pathology [14 months]

神经退行性机制

胶质细胞功能研究

GRN haploinsufficiency causes frontotemporal lobar degeneration and results in microglial hyperactivation, lysosomal dysfunction and TDP-43 deposition. To understand the contribution of microglial hyp

NIAID Data Ecosystem30

Imaging resident and recruited macrophage contributions to Wallerian degeneration. Imaging resident and recruited macrophage contributions to Wallerian degeneration

神经退行性机制

巨噬细胞功能组学

Abstract: Wallerian degeneration (WD) is a process of autonomous distal degeneration of axons upon injury. Macrophages (MP) of the peripheral nervous system (PNS) are main cellular agent controlling t

NIAID Data Ecosystem100

TDP-43 Inclusion Bodies Formed in Bacteria Are Structurally Amorphous, Non-Amyloid and Inherently Toxic to Neuroblastoma Cells

TDP-43蛋白聚集

神经退行性机制

Accumulation of ubiquitin-positive, tau- and α-synuclein-negative intracellular inclusions of TDP-43 in the central nervous system represents the major hallmark correlated to amyotrophic lateral scler

NIAID Data Ecosystem30

Aggregated proteome of MDK model mice

资源简介：

相关数据集