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Genome-wide maps of Argonaute 2-chromosome interactions in miR-204-3p-overexpressed macrophages [ChIP-Seq]

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NIAID Data Ecosystem2026-03-14 收录
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Ago2, an essential effector for miRNA function, has been reported to be found in the nucleus together with miRNA. The miRNA-Ago complexes in the nucleus play an important role in regulating gene transcription. We previously have demonstrated the nuclear presence of miR-204-3p in macrophages. Here, we investigated and compared the Ago2 occupancy on the chromosomes upon miR-204-3p overexpression. Examination of Ago-DNA interactions in human macrophages

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2022-09-16
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