Data for: SNPs detected in pool-seq data from resistant and susceptible Cimex lectularius populations

In the last few years, the bed bug Cimex lectularius has been an
increasing problem world-wide, mainly due to the development of
insecticide resistance to pyrethroids. The characterization of
resistance alleles is a prerequisite to improve surveillance and
resistance management. To identify genomic variants associated
with pyrethroid resistance in Cimex lectularius, we compared the
genetic composition of two recent and resistant populations with
that of two ancientsusceptible strains using a genome-wide
pool-seq design. We identified a large 6 Mb
"superlocus" showing particularly high genetic
differentiation and association with the resistance phenotype.
This superlocus contained several clustered resistance genes,
andwas also characterized by a high density of structural
variants (inversions, duplications). The possibility that this
superlocus constitute a resistance "supergene" that
evolved after the clustering of alleles adapted to insecticide
and after reduction in recombination is discussed.