Induction of cytokines one day after triggering TLR7 and/or 8 in PBMC; indicated in each box upper line are the average±std fold induction# and lower line the corresponding absolute concentrations of cytokines measured in the supernatant [pg/ml] (n = 3) ¶.

* ¥ IFN-α, IFN-γ, IL-6, IL-8, MIP-1α, MIP-1β, RANTES were measured by enzyme immunoassays, IL-12(p40) and TNF-α were measured with a bead assay (see material and method section).