Vaccine potential of the Y. pestis Kim53��nlpD strain against pneumonic plague.
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aMice were immunized subcutaneously with the indicated dose of each strain.bAnti-F1 and anti-V titers were determined by ELISA.cFifty days post immunization, mice were challenged intranasally with 10 LD50 of the virulent Y. pestis Kimberley53 strain (1 LD50 = 550 cfu).dUnder the specific experimental conditions, one colony forming unit of Kim53��nlpD is estimated to be 1-6 bacilli.
创建时间:
2015-12-02



