Attack rates and survival times (±SEM) of the inoculated <i>TgRab</i> mice.

aAnimals were considered TSE positive when spongiform lesions and/or PrPd was detected, either through IHC, WB or ELISA. Inconclusive results were confirmed by using more than one PrPd detection method. ND: Not determined, SEM: Standard Error of the Mean, NBH: Normal Brain Homogenate. bAll animals TSE negative. Age at death of the oldest animal of the group (spontaneous deaths or humanely euthanized due to non-TSE causes). Individual survival times are shown in Fig 1. cOne animal, euthanized at 742dpi, showed a positive result to PrPd ELISA but negative to the remaining tests (WB, IHC, HP) a second passage is ongoing. Attack rates and survival times (±SEM) of the inoculated TgRab mice.