Pleiotropic impact of DNA-PK in cancer and implications to therapeutic strategies. Pleiotropic impact of DNA-PK in cancer and implications to therapeutic strategies
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA480169
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资源简介：
DNA-dependent protein kinase catalitic subunit (DNA-PK) is associated with aggressive disease. DNA-PK plays a role in transcriptional regulation of cancer-relevent pathways but it is not well understood. This study uses transcriptomic analyses to understand the transcriptional role of DNA-PK in castration resistent prostate cancer (CRPC) upon DNA-PK inhibition Overall design: Transcriptional alterations upon DNA-PK inhibition were assessed through RNA-Seq of C4-2 prostate cancer cells Transcriptional alterations upon DNA-PK inhibition were assessed through RNA-Seq of 22RV1 prostate cancer cells
创建时间：
2018-07-08
