Quantitative phosphoproteomics results for PKN2 cardiomyocyte-specific knockout embryonic mouse hearts

DescriptionThis dataset contains phosphopeptide-level differential abundance results from quantitative mass spectrometry–based phosphoproteomics of embryonic mouse hearts comparing PKN2 cardiomyocyte-specific knockout (cKO) and control embryos.Phosphorylated peptides were identified and quantified by TMT-based LC–MS/MS. Differential abundance between genotypes was calculated using statistical modeling of normalized reporter ion intensities. The table includes phosphosite identifiers, protein annotations, fold-change estimates, and statistical significance values.Column descriptionsname – Phosphosite identifier composed of protein name and modified residue position.ID – Unique identifier combining the UniProt protein accession and phosphorylation site.protein.name – Gene symbol of the protein containing the phosphorylation site.protein.ID – UniProt accession number of the protein.sites – Phosphorylated residue and its position within the protein sequence.cKO_vs_Control_p.val – Raw p-value from the statistical test comparing phosphopeptide abundance between PKN2 cardiomyocyte knockout (cKO) and control samples.cKO_vs_Control_p.adj – Adjusted p-value (false discovery rate, FDR) after multiple testing correction.significant – Logical indicator (TRUE/FALSE) specifying whether the phosphosite passes the significance threshold after adjustment.cKO_vs_Control_significant – Logical indicator (TRUE/FALSE) specifying whether the phosphosite is considered significantly different between cKO and control in this comparison.cKO_vs_Control_ratio – Estimated fold change ratio of phosphopeptide abundance in cKO relative to control.Control_centered – Mean-centered normalized abundance value for the phosphopeptide in the control samples.cKO_centered – Mean-centered normalized abundance value for the phosphopeptide in the PKN2 cKO samples.