Crystal structure the Fab fragment of matuzumab (Fab72000) in complex with domain III of the extracellular region of EGFR

Crystal structure the Fab fragment of matuzumab (Fab72000) in complex with domain III of the extracellular region of EGFR Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, Matuzumab Fab Heavy chain, ... Authors: Ferguson, K.M, Schmiedel, J, Knoechel, T. Deposit date: 2008-01-18 Release date: 2008-04-15 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Matuzumab binding to EGFR prevents the conformational rearrangement required for dimerization. Cancer Cell, 13, 2008