Genome-wide maps of chromatin state in human primary airway smooth muscle cells.. Homo sapiens

We generated genome-wide chromatin-state maps of human airway smooth muscle cells. We find that lysine 4 and lysine 27 trimethylation effectively discriminates genes that are expressed, poised for expression, or stably repressed, Lysine 4 monomethylation was used to highlight the location of potential regulatory domains in these cells. Overall design: Examination of 3 different histone modifications in primary human cells.