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Human MAIT and CD8++ cell development
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创建时间:
2012-01-25
相关数据集
Development of Double-positive Thymocytes at Single-cell Resolution. Development of Double-positive Thymocytes at Single-cell Resolution
We applied single-cell sequencing to mouse thymocytes and analyzed the transcriptome data using Seurat. By applying unsupervised clustering, we defined thymocyte subtypes and validated DP cell subtype
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Unraveling human T cell development using scRNA-seq
T cells develop in the thymus from multipotent lymphoid precursors. During this gradual differentiation process thymocytes go through several decision points, before they fully mature into conventiona
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ROR?t? Dendritic Cells Are a Distinct Lymphoid-Derived Lineage [CITE-seq]
How tolerogenic dendritic cell (DC) lineages are established to prevent inappropriate immune responses to commensals and food antigens remains unclear. We identify ROR?t? DCs in mice as a distinct lym
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Examination of gene expression in different populations of the embryonic thymus at E15.5 and E19.5 by bulk RNA-seq
ILC2 contribute to immune homeostasis, protective immunity and tissue repair. However, an understanding of the microenvironmental factors and transcriptional circuits that support development of thes
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Cis-regulation between Irf8 enhancers during cDC1 development (ATAC-Seq). Cis-regulation between Irf8 enhancers during cDC1 development (ATAC-Seq)
Type 1 classical dendritic cells (cDC1s) development requires the transcription factor IRF8, and IRF8 mutations cause severe combined immunodeficiency, including disseminated bacille Calmette-Guérin (
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