The 13 markedly overexpressed mitotic spindle checkpoint genes in HCC samples.

*shown is mutated number of total HCC samples stored in COSMIC (Catalogue of Somatic Mutations In Cancer, http://cancer.sanger.ac.uk/cancergenome/projects/cosmic/), which collects somatic mutation information in human cancers. †Gene expression difference between these HCC cells and their derivative sorafenib-resistant cell sublines was evaluated by realtime quantitative PCR, where β-actin gene was used as an endogenous control. Statistical significance of gene expression difference was calculated using Student’s t test.