We have generated gliomas (brain tumours) in mice using an EGFR conditional mutation and / or piggybac transposon insertional mutagenesis. In order to identify genetic mutations required for evolution
The project aimed to generate transgenic mouse models for the two major human multiple myeloma (MM) subgroups. The models are based on the specific overexpression of MMSET or Ccnd1 and Ikk2ca in mouse
The project aimed to generate transgenic mouse models for the two major human multiple myeloma (MM) subgroups. The models are based on the specific overexpression of MMSET or Ccnd1 and Ikk2ca in mouse