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Integrated multiplex PCR and metatranscriptomics reveal upper-lower airway microbial landscapes in pediatric respiratory infections

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DataCite Commons2026-01-30 更新2026-05-05 收录
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https://www.scidb.cn/detail?dataSetId=db4b5956221e46928bcff1e56d342316
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Respiratory samples were collected from 514 hospitalized pediatric patients diagnosed with ARTIs. A total of 505 nasopharyngeal swabs (NS) and 85 bronchoalveolar lavage fluid (BALF) samples were obtained.  NS and BALF samples were tested using a 22-target multiplex PCR panel and subsequently stratified by pathogen status for pooled metatranscriptomic sequencing to profile active microbial communities, viral genotypes, and antibiotic resistance genes.
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Science Data Bank
创建时间:
2026-01-30
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