Exercise-associated gut microbiota contributes to the beneficial effect of Exe on sepsis.

For exercise training, mice were randomly assigned to two activity groups: exercise training (Exe) or sedentary control (Ctrl). The Exe mice underwent a treadmill exercise routine as described previously, starting at 5 meters (m) per minute for 10 minutes and then increasing to 15 m per minute for 60 minutes once daily for 14 days. In contrast, the Ctrl mice were housed in cages without any physical activity.