Prostate cancer androgen receptor activity dictates efficacy of bipolar androgen therapy through MYC

NIAID Data Ecosystem2026-05-01 收录

前列腺癌靶向治疗

激素受体机制研究

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE213444 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2024-01-16

Discovery of Potent DYRK2 Inhibitors with High Selectivity, Great Solubility, and Excellent Safety Properties for the Treatment of Prostate Cancer

前列腺癌靶向治疗

DYRK2

Prostate cancer (PCa) is a common male cancer with high incidence and mortality, and hormonal therapy as the major treatment for PCa patients is troubled by the inevitable resistance that makes us ide

NIAID Data Ecosystem100

前列腺癌靶向治疗

雄激素受体拮抗剂机制

The androgen receptor (AR) surface-directed antagonist MJC13 inhibits AR function and proliferation of prostate cancer (PC) cells. These effects are related to arrest of an AR/chaperone complex in the

Figshare2016-01-15 更新50

Reversal of lineage plasticity in RB1/TP53-deleted prostate cancer through FGFR and Janus kinase inhibition. Reversal of lineage plasticity in RB1/TP53-deleted prostate cancer through FGFR and Janus kinase inhibition

前列腺癌靶向治疗

肿瘤谱系可塑性

The inherent plasticity of tumor cells provides a mechanism of resistance to many molecularly targeted therapies, exemplified by adeno-to-neuroendocrine lineage transitions seen in prostate and lung c

NIAID Data Ecosystem40

Physachenolide C is a Potent, Selective BET Inhibitor

BET抑制剂

前列腺癌靶向治疗

A pulldown using a biotinylated natural product of interest in the 17β-hydroxywithanolide (17-BHW) class, physachenolide C (PCC), identified the bromodomain and extra-terminal domain (BET) family of p

Figshare2022-12-28 更新80

Supplementary Table from Squalene Epoxidase Metabolic Dependency Is a Targetable Vulnerability in Castration-Resistant Prostate Cancer

前列腺癌靶向治疗

代谢研究

Supplementary Table from Squalene Epoxidase Metabolic Dependency Is a Targetable Vulnerability in Castration-Resistant Prostate Cancer

NIAID Data Ecosystem40