One-Pot Organocatalytic Enantioselective Domino Double-Michael Reaction and Pictet-Spengler–Lactamization Reaction. A Facile Entry to the “Inside Yohimbane” System with Five Contiguous Stereogenic Centers
收藏NIAID Data Ecosystem2026-03-07 收录
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资源简介：
An expedited method was developed for the enantioselective synthesis of dodecahydrobenz[a]indolo[3,2-h]quinolizine containing five contiguous stereogenic centers with high enantioselectivities (>99% ee). The methodology comprises a domino organocatalytic double Michael reaction and Pictet-Spengler–lactamization reaction. The structures and absolute configurations of the appropriate products were confirmed by X-ray analysis.
创建时间：
2016-02-20
