Evolution of common gene output according to EV occurence.

Each possible EV occurrence stringency level was tested, i.e. from = 6/6 down to ≥3/6. EV analysis provides “Gene output” in the second column. Using Ingenuity Pathway Analysis software we obtained the following data. The “Eligible Network” column which gives the number of genes belonging to a network. The “Common Genes” column represents the total number of genes which have been found in at least two different networks. The “Common gene %” column provides the percentage of genes shared by different networks. The next column gives the total number of genes in the main network, from which it is possible to calculate the number of specific genes (genes in the main network minus genes common to at least two networks). The second last column presents specific genes as the percentage of all genes in the main network (column Gene % in main network). Finally, the table displays the “best score of the main network” for each stringency level.