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Celf1 and Postnatal Lens Microarray

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Celf1 germline or conditional deletion mouse mutants exhibit fully penetrant lens defects including cataract. To gain insight into gene expression changes underlying these lens defects, microarray comparison was performed for lenses obtained from control and Celf1 conditional deletion mutant mice. Microarray comparison of lenses from mixed background (C57BL/6J, FVB) control (Celf1lacZKI/+)and mutant (Celf1cKO) mice was performed

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