Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4

NIAID Data Ecosystem2026-05-01 收录

表观遗传调控

氨基酸代谢通路

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE245830 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2023-11-20

PBRM1 bromodomains associate with RNA to facilitate chromatin association (CLIP-seq). PBRM1 bromodomains associate with RNA to facilitate chromatin association (CLIP-seq)

PBRM1RNA结合机制

表观遗传调控

PBRM1 is a subunit of the PBAF chromatin remodeling complex, which is mutated in 40-50% of clear cell renal cell carcinoma patients. It is thought to largely function as a chromatin binding subunit of

NIAID Data Ecosystem30

RNA demethylase ALKBH5 regulates cell cycle progression in X-ray-induced DNA damage response

DNA损伤修复

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RNA N6-methyladenosine (m6A) modification plays a crucial role in the DNA damage response, while the detailed mechanisms remain to be explored. In this study, we report the involvement of the m6A deme

NIAID Data Ecosystem00

Epigenetic silencing by SMYD3 represses tumor intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck [RNA-seq]. Epigenetic silencing by SMYD3 represses tumor intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck [RNA-seq]

头颈鳞状细胞癌免疫

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Cancers often display immune escape, but the mechanisms and potential for reversibility are incompletely understood. Epigenetic dysregulation has been implicated in the immune escape of various cancer

NIAID Data Ecosystem00

KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity [RNA-seq]

表观遗传调控

基因表达抑制

CpG islands (CGI) are associated with the majority of mammalian gene promoters and function to recruit chromatin modifying enzymes. It has therefore been proposed that CGIs regulate gene expression th

NIAID Data Ecosystem00

A natural bacterial pathogen of C. elegans uses a small RNA to induce transgenerational inheritance of learned avoidance

宿主-微生物相互作用

表观遗传调控

A small RNA from Pseudomonas aeruginosa, PA14, induces learned avoidance and its transgenerational inheritance in C. elegans. However, it is not known if small RNAs from bacteria found in C. elegans'

NIAID Data Ecosystem00

Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4

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