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Crystal structure of human TEAD2-Yap binding domain covalently bound to an allosteric regulator

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal structure of human TEAD2-Yap binding domain covalently bound to an allosteric regulator Descriptor: 1-(2-{[3-(trifluoromethyl)phenyl]amino}phenyl)ethan-1-one, Transcriptional enhancer factor TEF-4 Authors: Bum-Erdene, K, Gonzalez-Gutierrez, G, Meroueh, S.O. Deposit date: 2018-07-20 Release date: 2019-01-09 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.43 Å) Cite: Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction. Cell Chem Biol, 26, 2019
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2018-07-20
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