Supplementary Table 2 from The Tumor Suppressive MicroRNA <i>miR-218</i> Targets the mTOR Component <i>Rictor</i> and Inhibits AKT Phosphorylation in Oral Cancer
Oral carcinogenesis is a multi-step process involving normal mucosa progressing to oral precancerous lesions and finally to oral squamous cell carcinoma (OSCC). This complex process encompasses variou
A tight control over AKT/PKB activation is essential for cells, and they realise this in part by regulating the phosphorylation of Ser473 in the “hydrophobic motif” of the AKT carboxy-terminal region.