Total Synthesis of (−)-Nahuoic Acid C<sub>i</sub> (B<sub>ii</sub>)
收藏NIAID Data Ecosystem2026-03-10 收录
数据链接：
官方服务：
资源简介：
A convergent total synthesis of (−)-nahuoic acid Ci(Bii) (3), a novel cis-decalin polyketide, has been achieved. Key synthetic transformations include Type II Anion Relay Chemistry (ARC) to construct the polyol chain, a Ti-catalyzed asymmetric Diels–Alder reaction to generate the cis-decalin skeleton, and a late-stage large fragment union exploiting a Micalizio alkoxide-directed alkyne–alkene coupling tactic.
创建时间：
2017-09-21
