Targeting NHE6 gene expression identifies lysosome and neurodevelopmental mechanisms in Christianson Syndrome cell model. Targeting NHE6 gene expression identifies lysosome and neurodevelopmental mechanisms in Christianson Syndrome cell model

To investigate the function NHE6 protein, we established HAP1 CRISPR-CAS9 SLC9A6 Knockout lines and their paired controls . We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 different cells, each with 6 replicates, at two time points. Overall design: Comparative gene expression profiling analysis of RNA-seq data for HAP1 cells and its SLC9A6 CRIPSR/Cas9-mediated genome editing mutant.