官方服务：
资源简介：
Human viral targets of CRISPR/Cas9.
应用场景：
创建时间：
2016-12-09
相关数据集
Alkyne Derivatives of SARS-CoV‑2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine
Nirmatrelvir (PF-07321332) is a nitrile-bearing small-molecule inhibitor that, in combination with ritonavir, is used to treat infections by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2
NIAID Data Ecosystem80
Receptor Tyrosine Kinase Inhibitors Block proliferation of coronavirus mainly through p38 mitogen-activated protein kinase pathways
Emerging coronaviruses (CoVs) primarily cause severe gastroenteric or respiratory diseases in humans and animals, for which no approved therapeutics are available so far. Here A9, a receptor tyrosine
NIAID Data Ecosystem70
Strongest PAMs considering only standard DNA base designations.
Strongest PAMs considering only standard DNA base designations.
NIAID Data Ecosystem20
HIV‑1 gp120 Antagonists Also Inhibit HIV‑1 Reverse Transcriptase by Bridging the NNRTI and NRTI Sites
HIV-1 infection is typically treated using ≥2 drugs, including at least one HIV-1 reverse transcriptase (RT) inhibitor. Drugs targeting RT comprise nucleos(t)ide RT inhibitors (NRTIs) and non-nucleo
NIAID Data Ecosystem70
CELL-REPORTS-D-25-03172
Hypothesis: Flavitrasin (FT) is a selective Sec61 inhibitor of dengue virus (DENV)/ Orthoflavivirus polyprotein translocation. We report the antiviral activity of the CADA derivative VGD020, renamed
NIAID Data Ecosystem50
