Patients’ clinical information.

Endometriosis is a chronic inflammatory gynaecological condition frequently associated with chronic pelvic pain. Visceral hypersensitivity could be present, like in other chronic pain conditions, causing altered levels of interoception. So far, studies have explored interoceptive deficits in chronic pain individuals mainly using questionnaires or cardiac interoceptive accuracy tasks. Here, we explore the cardiac, gastric, and urinary domains to probe interoceptive differences between patients with endometriosis and healthy women. 30 patients and 30 controls underwent three interoceptive tasks for assessing the cardiac domain (using the Heartbeat Counting Task, HCT), the gastric domain (using the Water Load Test-II, WLT-II) and the bladder domain (using a novel Urinary Interoceptive Task, UIT). Participants also completed bladder interoceptive beliefs measures and subjective pain ratings for each endometriosis symptom (dysmenorrhea, dyspareunia, dyschezia, chronic pain). A positive correlation between the WLT-II and the UIT emerged in all participants (R = 0.47, p