Shared additive genetic effects within a pathway of conditionally correlated probes.

* is the proportion of additive variance explained by the eSNP.
**To further demonstrate a genetic causal link between probes, the eSNP from the primary probe was included as a linear covariate in the family based analysis (model [1]). Heritability estimated from this model is conditional on the eSNP genotypes; the difference in compared to the model not including the eSNP represents the proportion of accounted for by the eSNP for the conditionally correlated probes.