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Mutational profile of mismatch repair deficiency

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NIAID Data Ecosystem2026-04-25 收录
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Mismatch repair gene MSH2 was knocked out from the MCF10A human cell line. Mutations that accumulated in the knockout cells after 105 population doublings were determined by whole exome sequencing using the Agilent SureSelectXT2 Human All Exon V6 library kit and the Illumina HiSeq platform.

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2020-12-01
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