Tetraethylammonium Salts as Solid, Easy to Handle Ethylene Precursors and Their Application in Mizoroki–Heck Coupling

Analytical Data and Compound Numbering (in paper numbering vs. ELN entries) for the Publication entitled:"Tetraethylammonium Salts as Solid, Easy to Handle Ethylene Precursors and Their Application in Mizoroki−Heck Coupling"

The paper was published on 2024-03-11 in The Journal Organic Chemistry

J. Org. Chem. 2024, 89, 5126−5133

DOI: 10.1021/acs.joc.3c02867

Authors: Eleni Papaplioura, Maëva Mercier, Michael E. Muratore, Tobias Biberger, Soufyan Jerhaoui, Michael Schnürch

This project has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie, Grant Agreement No. 860762.

Context and methodology

In this study, we introduce a convenient Heck vinylation protocol that eliminates the requirement for ethylene gas as a coupling partner. In contrast to traditional methodologies, quaternary ammonium salts can serve as solid olefin precursors under ambient atmosphere conditions. The practicality of this method, distinguished by its convenience and safety in a one-pot reaction, renders it appealing for applications in research and discovery context.

The publication and its Supporting Information can be found as open-access files on the publisher's website (see DOI above).

All detailed files containing the analytical raw data, for all compounds given in the Supporting Information of the manuscript are uploaded. An additional PDF file named J. Org. Chem. 2024 compound number list.docx is uploaded, that should clearly link the compound number given in the paper to the respective entry in the ELN (jotempl) and the respective analytical data files. 

Technical details

The files uploaded contain the FIDs of NMR spectra recorded by an in-house Bruker Spectrometer. A software to display NMR-spectra is needed, such as MestreNova or Topspin).

HRMS data is uploaded too and has to be processed via MassHunter software.