Reproducibility Package for Fractional-Order Dynamics and Adaptive Network Feedback in a Mathematical Model of Alzheimer's Disease

This repository provides numerical simulation code, generated datasets, network adjacency information and reproducibility resources supporting the manuscript "Fractional-Order Dynamics and Adaptive Network Feedback in a Mathematical Model of Alzheimer's Disease", prepared for submission to BioSystems. The model combines Caputo fractional-order equations for amyloid-beta burden, tau pathology, glial activation and neural population activity with an ordinary differential equation describing adaptive directed connectivity. The repository includes Python implementations, reference parameters, network-generation information, numerical trajectories, verification scripts and figure-generation resources. All numerical datasets are generated from the mathematical model. No patient-level, clinical or ADNI data are included. The accompanying documentation describes the numerical methods, file structure and available reproduction procedures.