Supramolecular Architecture Consisting of an Enantiopure Amine and an Achiral Carboxylic Acid: Application to the Enantioseparation of Racemic Alcohols

Three-dimensionally dissymmetric cavities are created from an enantiopure amine and an achiral carboxylic acid, which can incorporate the
third components to realize the formation of closely packed crystals. The combination demonstrates enantioselective inclusion for 20 kinds
of racemic alcohols. The inclusion phenomenon occurs not only during crystallization but also in the solid state.