Effect of gestational diabetes mellitus on intestinal flora and its effect on congenital kidney malformation through gpr43 pathway

Bioinformatics analysis combined with in vitro and in vivo experiments revealed the characteristics of intestinal flora and metabolic differences in patients with gestational diabetes mellitus (GDM), and the mechanism of affecting gpr43 pathway and thus affecting the offspring's congenital anomalies of the kidney and the urinary tract (CAKUT)