Structural insights into the cryptic DNA dependent ATP-ase activity of UvrB

NIAID Data Ecosystem2026-05-01 收录

DNA损伤修复

蛋白质结构与功能

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Structural insights into the cryptic DNA dependent ATP-ase activity of UvrB

创建时间：

2023-10-25

Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

NIAID Data Ecosystem40

Borrowed proteins in bacterial bioluminescence.

微生物发光

蛋白质结构与功能

A library of Photobacterium phosphoreum DNA was screened in lambda 2001 for the lumazine protein gene, using two degenerate 17-mer oligonucleotide probes that were deduced from a partial protein prima

PubMed Central1991-02-15 更新20

p38-MK2 regulate RNA metabolism after UV light-induced DNA damage

DNA损伤修复

转录调控

Ultraviolet (UV) light induces the formation of bulky UV photoproducts in the genome that interfere with DNA replication and transcription. It is well-established how human cells repair UV light-induc

NIAID Data Ecosystem20

Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase

DNA损伤修复

跨损伤合成

Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase Descriptor: 2-AMINOFLUORENE, DNA polymerase I, DNA primer strand, ... Authors: Hsu, G.W, Kiefer, J.R, Becherel, O.J, Fuchs, R.P.P

Protein Data Bank Japan2023-08-23 更新30

Pseudomonas stutzeri nitrous oxide reductase mutant, H129A

氧化亚氮还原酶突变体

蛋白质结构与功能

Pseudomonas stutzeri nitrous oxide reductase mutant, H129A

NIAID Data Ecosystem20