Expression data for human peripheral blood mononuclear cells (PBMCs) transfected with EBV Bart 6-3p mimics.

Epstein-Barr virus (EBV) is highly successful virus infecting the majority of the human population worldwide. During the latent infection period, there are only a few of EBV-encoded proteins can be detected, whereas EBV-encoded non-coding RNAs are highly activated, especially microRNAs. Recent studies found that those BART microRNAs not only disturb EBV genes expression, but also interfere many host genes expression, thus modulating cellular proliferation and immune regulation. In the present study, we investigate the effect of EBV BART6-3p on gene expression profile of the human PBMCs. Human PBMCs from a health donor were transfected with a control mimics or EBV BART6-3p mimics (150 μM) for 36 hours. Total RNA were extracted and detected by Affymetrix Human Genome U133 Plus 2.0 Array.