Crystal structure of YfiA bound to the 70S ribosome. Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... Authors: Polikanov, Y.S, Blaha, G.M, Steitz, T.A. Deposit date: 20

Protein Data Bank Japan2024-10-30 更新20

The Gcn4 Transcription Factor Reduces Protein Synthesis Capacity and Extends Yeast Lifespan. The Gcn4 Transcription Factor Reduces Protein Synthesis Capacity and Extends Yeast Lifespan

酵母寿命调控

蛋白质合成抑制

In Saccharomyces cerevisiae, deletion of genes encoding proteins of the large ribosomal subunit (RPLs) increases the replicative lifespan in a Gcn4-dependent manner. However, how Gcn4, a key transcrip

NIAID Data Ecosystem30

A novel antimalarial agent that inhibits protein synthesis in Plasmodium falciparum

抗疟药物研发

蛋白质合成抑制

Drug resistance to nearly all antimalarials following their rollout underscores the need for novel chemotypes with novel mode of action to replenish the antimalarial drug-development pipeline. We iden

NIAID Data Ecosystem20

%-ΔcGI Cycloheximide.

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