The protein homeostasis (proteostasis) network maintains balanced protein synthesis, folding, transport and degradation within a cell. Because failure to maintain proteostasis is associated with aging

NIAID Data Ecosystem20

Proteasome inhibition and oxidative biochemistry are synergistic triggers of metabolic heme toxicity (part 1)

血红素毒性机制

蛋白质稳态

Control of intracellular heme levels by extracellular scavenger proteins and intracellular heme oxygenases are essential functions during disease states with enhanced extracellular heme release. Durin

NIAID Data Ecosystem30

Data_Sheet_1_Synonymous mutations in the phosphoglycerate kinase 1 gene induce an altered response to protein misfolding in Schizosaccharomyces pombe.PDF

蛋白质稳态

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BackgroundProteostasis refers to the processes that regulate the biogenesis, folding, trafficking, and degradation of proteins. Any alteration in these processes can lead to cell malfunction. Protein

NIAID Data Ecosystem20

RNA coimmunoprecipitations

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