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Crystal structure of streptogramin A acetyltransferase VatA from Staphylococcus aureus in complex with streptogramin analog F1037 (47)

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Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Crystal structure of streptogramin A acetyltransferase VatA from Staphylococcus aureus in complex with streptogramin analog F1037 (47) Descriptor: (3R,4R,5E,10E,12E,14S,16R,26aR)-16-fluoro-14-hydroxy-12-methyl-3-(propan-2-yl)-4-(prop-2-en-1-yl)-3,4,8,9,14,15,16,17,24,25,26,26a-dodecahydro-1H,7H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,22-trione, CHLORIDE ION, MAGNESIUM ION, ... Authors: Chaires, H.A, Fraser, J.S. Deposit date: 2020-05-21 Release date: 2020-11-18 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.05 Å) Cite: Synthetic group A streptogramin antibiotics that overcome Vat resistance. Nature, 586, 2020
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2020-05-21
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