Comparison of bulk RNAseq results of WT and TKO E14 EpiLCs

We investigate the impact of DNA methylation on epiblast differentiation. To this end, we used in vitro Epiblast-like cell (EpiLC) differentiation on WT and DNA-methylation free TKO murine ESCs. We next performed bulk RNAseq at D0, D2, D4, D6 and D8 of differentiation to study transcriptomic differences. Overall design: Bulk mRNA sequencing on WT and TKO ESCs (D0), and D2, D4 and D7 cells during EpiLC differentiation