Cryptococcus neoformans thymidylate synthase complexed with substrate and an antifolate

Cryptococcus neoformans thymidylate synthase complexed with substrate and an antifolate Descriptor: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase Authors: Finer-Moore, J.S, Anderson, A.C, O'Neil, R.H, Costi, M.P, Ferrari, S, Krucinski, J, Stroud, R.M. Deposit date: 2005-07-14 Release date: 2005-12-06 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.08 Å) Cite: The structure of Cryptococcus neoformans thymidylate synthase suggests strategies for using target dynamics for species-specific inhibition. Acta Crystallogr.,Sect.D, 61, 2005