Dynamic Data Independent Acquisition Mass Spectrometry with Real-Time Retrospective Alignment
收藏DataCite Commons2023-02-05 更新2025-04-17 收录
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https://panoramaweb.org/dynamicDIA.url
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资源简介：
We report a data independent acquisition (DIA) strategy that dynamically adjusts the tandem mass spectrometry (MS/MS) windows during the chromatographic separation. The method focuses MS/MS acquisition on the most relevant mass range at each point in time – improving the quantitative sensitivity by increasing the time spent on each DIA window. We demonstrate an improved lower limit of quantification, on average, without sacrificing the number of peptides detected.
提供机构：
Panorama Public
创建时间：
2022-12-02
