Segatella copri complex

The Segatella copri (formerly Prevotella copri) complex (ScC) comprises taxa that are key members of the human gut microbiome. It was previously described to contain four distinct clades. Combining targeted isolation with large-scale metagenomic analysis, we expanded the ScC defining 13 distinct bacterial species. The nine species present in humans display striking differences in prevalence and intra-species genetic makeup across human populations. Our work uncovers previously overlooked genomic diversity within the ScC instrumental for better characterization of the human microbiome. Please see additional genomic data in Bioproject PRJNA684333 form Li, et. al. EMBO J (2021) 40: e108287