Understanding the transcriptional consequences of the Progeria LmnaG609G mutation within the immune compartment of the lung using single cell RNA sequencing.

To understand the transcriptional consequences of Progeria LmnaG609G mutation within the immune compartment of the lung we conducted single cell RNA sequencing on sorted immune cells from WT vs. LmnaG609G/G609G mice (in duplicate, 2 mice per group). Overall design: WT and LmnaG609G/G609G lung immune cells were subjected to single cell RNA sequencing.