Iron-Catalyzed 1,5-Enyne Cycloisomerization via 5-Endo-Dig Cyclization for the Synthesis of 3‑(Inden-1-yl)indole Derivatives
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An Fe(OTf)3-catalyzed 1,5-enyne cycloisomerization via 5-endo-dig cyclization is described for the synthesis of 3-(1-indenyl)indole derivatives. Since a variety of 1,5-enynes are readily accessible via Heck–Suzuki coupling, this strategy provides a rapid and easy access to a wide range of highly substituted 3-(1-indenyl)indoles in good yields.
创建时间:
2016-12-07



