Deconvoluted methylation profiles discriminate between closely related melanocytic nevi

Congenital melanocytic nevi (CMN) and common acquired melanocytic nevi (AMN) are skin conditions that result from an excess of melanocytes arising during fetal development or detected postnatally. Appropriately weighted whole-genome methylation analysis can be used as a basis for further research in dermatopathology and, in this application, provides new insights into nevus biology. To investigate molecular differences between congenital melanocytic nevi (CMN) and acquired melanocytic nevi (AMN) through the study of their DNA methylation profiles Please note that the processed data files (containing beta values) have been updated on Oct 2, 2024.