Characterization of microRNA in cow milk and colostrum
收藏DataCite Commons2025-05-12 更新2025-04-15 收录
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https://dataverse.harvard.edu/citation?persistentId=doi:10.7910/DVN/X3JJOL
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资源简介：
MicroRNAs (miRNAs) are short RNA molecules,
typically 21 to 25 nucleotides long, synthesized within
eukaryotic cells. They play a crucial role in coordinating
complex gene expression regulatory networks. The
miRNAs are involved in post-transcriptional regulation,
either by degrading target mRNA or suppressing their
transcription, thereby influencing protein translation.
Additionally, characteristics of farm production systems
exert a noticeable influence on miRNA profiles, shaping
the functional properties of bovine milk. In this study,
milk and colostrum samples of Holstein cows (Bos taurus)
were collected for RNA extraction and sequencing.
Sequencing data underwent quality controls, and short
noncoding RNA reads were analyzed to identify and
compare miRNA profiles. The sequencing runs yielded
73,567,661 and 44,283,978 reads for milk and colostrum
samples, respectively. Following trimming, 8,335,860
and 7,778,212 reads for milk and colostrum samples
were retained. A total of 4.3% milk and 37.8% colostrum
reads were identified as miRNAs.
提供机构：
Harvard Dataverse
创建时间：
2025-01-21
