Data from: Comparison of regional gene expression differences in the brains of the domestic dog and human

Comparison of the expression profiles of 2,721 genes in the cerebellum,
cortex and pituitary gland of three American Staffordshire terriers, one
beagle and one fox hound revealed regional expression differences in the
brain but failed to reveal marked differences among breeds, or even
individual dogs. Approximately 85 per cent (42 of 49 orthologue
comparisons) of the regional differences in the dog are similar to those
that differentiate the analogous human brain regions. A smaller percentage
of human differences were replicated in the dog, particularly in the
cortex, which may generally be evolving more rapidly than other brain
regions in mammals. This study lays the foundation for detailed analysis
of the population structure of transcriptional variation as it relates to
cognitive and neurological phenotypes in the domestic dog.