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Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE162623
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资源简介:
We report that loss of EZH2 provides leukaemia cells with a selective growth advantage, which mediates chemotherapy resistance. This resistance is conferred by up regulation of direct and indirect EZH2 target genes. Description of expression changes due to EZH2 knockout in K562 cells.
创建时间:
2021-03-23
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