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Intermolecular Interception of α‑Oxo Gold Carbenes of Nitroalkyne Cycloisomerization with 1,2-Benzo[d]isoxazole: Synthesis of Functionalized Quinazoline 1‑Oxides

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Figshare2021-07-27 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Intermolecular_Interception_of_Oxo_Gold_Carbenes_of_Nitroalkyne_Cycloisomerization_with_1_2-Benzo_i_d_i_isoxazole_Synthesis_of_Functionalized_Quinazoline_1_Oxides/15059852
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The known nitrogen-transfer reagent 1,2-benzo­[d]­isoxazole has been used to trap the postulated α-oxo gold carbene intermediate involved in the [Au]-catalyzed internal redox process of 2-alkynylnitrobenzenes. This process led us to develop a general convergent method for the synthesis of highly functionalized quinazoline 1-oxides.
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2021-07-27
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